Human/Rhesus macaque/Mouse/Rat/Canine BMP2 Protein

Name: Human/Rhesus macaque/Mouse/Rat/Canine BMP2 Protein
Brand: 普维拓生物
SKU: BMP2-HP001

货号BMP2-HP001

HumanE. coli分子名 · BMP-2理论分子量 · 12.90 kDa

产品简介

Recombinant Human/Rhesus macaque/Mouse/Rat/Canine BMP2 Protein is expressed in E. coli without tag. It contains amino acid residues Gln283-Arg396 (Human/Rhesus macaque) / Gln279-Arg393 (Mouse/Rat) / Gln282-Arg395 (Canine) (accession: P12643(Human) / G7N2Y0(Rhesus macaque) / P21274(Mouse) / P49001(Rat) / A0A8I3PXE9(Canine)).

产品详情

分子别名: BMP-2; BMP-2A; BMP2A; BDA2; SSFSC;
蛋白长度: Gln283-Arg396
表达系统: E. coli
理论分子量: The protein has a predicted MW of 12.90 kDa same as Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 0.5 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22μm filtered solution in 100mM Acetic Acid (pH 2.8). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in 100mM Acetic Acid (pH 2.8). Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Human/Rhesus macaque/Mouse/Rat/Canine BMP2 on Bis-Tris PAGE under Non reduced (N) condition and reduced condition. The purity is greater than 95%.

Cell Based Assay Data — Measured by its ability to induce Alkaline Phosphatase production by ATDC5 mouse chondrogenic cells. The ED50 for this effect is 100-400 ng/mL. (QC Test)

背景介绍

Bone morphogenetic protein 2 (BMP2), a member of the transforming growth factor-β (TGF-β) super-family, is one of the main chondrogenic growth factors involved in cartilage regeneration. BMP2 is known to induce chondrogenic differentiation in various types of stem cells in vitro. However, BMP2 also induces osteogenic differentiation and endochondral ossification in mesenchymal stem cells (MSCs).

文献引用

1.PMID: 27083447.

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Human/Rhesus macaque/Mouse/Rat/Canine BMP2 Protein

货号BMP2-HP001

HumanE. coli分子名 · BMP-2理论分子量 · 12.90 kDa

Human/Rhesus macaque/Mouse/Rat/Canine BMP2 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

Bioactivity

Cell Based Assay Data

背景介绍

文献引用

Human/Rhesus macaque/Mouse/Rat/Canine BMP2 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

Bioactivity

Cell Based Assay Data

背景介绍

文献引用