From molecular designto antibody candidates.

Connected recombinant protein and phage display workflows, built around traceable decisions and experimental evidence at every critical stage.

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Multi-system expression
Traceable milestones
Direct scientist access

Products

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Immune checkpoint proteins Biotinylated proteins Fc fusion proteins Antibody tools Cytokines & growth factors

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Technical services

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Protein production

From construct and host assessment through purification and sample delivery.

Recombinant antigen expressionExplore service

Phage display discovery

Selection strategy, library enrichment and clone validation for candidate discovery.

Selection strategy and feasibilityExplore service

Protein Production and Antibody Discovery Services

01Design

02Produce

03Select

04Characterize

PROTEIN PRODUCTION

Protein production

Mammalian, insect, yeast and bacterial systems
Secreted proteins, ECDs, Fc fusions and custom antigens
Purification development and agreed QC

Scale-up expression
Multiple production platforms
Process and batch consistency

Functional and physicochemical testing
Stability and impurity assessment

Structural and functional characterization
Quality and consistency review
Data and report archive

Explore protein expression

PHAGE DISPLAY

Antibody discovery

Antigen presentation and selection strategy
Library construction and quality review
Selection plan

Phage library amplification
Target coating and pre-selection
Library quality control

Iterative panning and enrichment
Positive clone screening
Affinity and functional triage

Candidate expression and purification
Activity and specificity testing
Sequence review and follow-up

Discuss an antibody project

PROTEIN PRODUCTION

Protein production

01Design

Mammalian, insect, yeast and bacterial systems
Secreted proteins, ECDs, Fc fusions and custom antigens
Purification development and agreed QC

02Produce

Scale-up expression
Multiple production platforms
Process and batch consistency

03Select

Functional and physicochemical testing
Stability and impurity assessment

04Characterize

Structural and functional characterization
Quality and consistency review
Data and report archive

Explore protein expression

PHAGE DISPLAY

Antibody discovery

01Design

Antigen presentation and selection strategy
Library construction and quality review
Selection plan

02Produce

Phage library amplification
Target coating and pre-selection
Library quality control

03Select

Iterative panning and enrichment
Positive clone screening
Affinity and functional triage

04Characterize

Candidate expression and purification
Activity and specificity testing
Sequence review and follow-up

Discuss an antibody project

Quality Control and Project Deliverables

Evidence index

Method

Test and record format

Project deliverables

Purity

Purity and molecular weight

Homogeneity

Homogeneity and aggregation

SDS-PAGE (reducing)

SEC / SEC-MALS

Purity report and gel image
SEC/SEC-MALS data and chromatogram
Batch test results

Homogeneity assessment
Aggregation analysis

Binding

Kinetics and affinity

Activity

Binding and functional activity

BLI / SPR Sensorgram

Activity (ELISA)

Homogeneity assessment
Aggregation analysis

Activity report
Source data and figures

Sequence

Candidate sequences and clustering

Sequencing (Sanger / NGS)

Clone sequence files
Sequence alignment and clustering

Project record

Strategy, process and milestones

Project management and data archive

Construct strategy

Process milestones

QC and release

Source data archive

Construct and purification strategy
Process milestone record
QC and release record
Source data and report archive

Specific deliverables are confirmed for each project scope and retained in traceable project records.

Start with your target and intended use

Share a sequence, target profile or existing antigen data. Our scientists will define the most productive starting point.

Start a project Contact our scientists

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