Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)

Name: Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)
Brand: 普维拓生物
SKU: VEGFR2-AB001

货号VEGFR2-AB001

HumanHEK293理论分子量 · 52.0 kDa

产品简介

Anti-VEGF R2 Antibody (Ramucirumab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target VEGF R2, reactivity Human/Rhesus macaque, isotype Human IgG1-Kappa, source-listed application ELISA.

产品详情

表达系统: HEK293
理论分子量: 52.0 kDa and 23.3 kDa.
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: PBS, 10% glycerol (pH 7.4)
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Ramucirumab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Ramucirumab Biosimilar is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human VEGF R2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Ramucirumab Biosimilar with the EC50 of 5.5/5.2ng/ml determined by ELISA. (QC Test)

背景介绍

The vascular endothelial growth factor receptor-2 (VEGFR-2/KDR/flk-1) functions as the primary mediator of vascular endothelial growth factor activation in endothelial cells. Regulation of VEGFR-2 expression appears critical in mitogenesis, differentiation, and angiogenesis. Transcriptional regulation of the VEGFR-2 is complex and may involve multiple putative upstream regulatory elements including E boxes.

文献引用

1.PMID: 15941713.

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Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用

Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用