Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

Name: Anti-Tissue Factor Antibody (Tisotumab Biosimilar)
Brand: 普维拓生物
SKU: TISSUEFACTOR-AB001

货号TISSUEFACTOR-AB001

HumanHEK293理论分子量 · 51.09 kDa

产品简介

Anti-Tissue Factor Antibody (Tisotumab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target Tissue Factor, reactivity Human/Cynomolgus, isotype Human IgG1-Kappa, source-listed application ELISA.

产品详情

表达系统: HEK293
理论分子量: 51.09 kDa and 23.37 kDa.
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: PBS, 10% glycerol (pH 7.4)
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Tisotumab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Tisotumab Biosimilar is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human Tissue Factor, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Tisotumab Biosimilar with the EC50 of 4.4ng/ml determined by ELISA. (QC Test)

背景介绍

Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.

文献引用

1.Rao LV. Tissue factor as a tumor procoagulant. Cancer Metastasis Rev. 1992 Nov;11(3-4):249-66. doi: 10.1007/BF01307181. PMID: 1423817.
2.Carmeliet P, Collen D. Tissue factor. Int J Biochem Cell Biol. 1998 Jun;30(6):661-7. doi: 10.1016/s1357-2725(97)00121-0. PMID: 9695023.

加载中…

Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

货号TISSUEFACTOR-AB001

HumanHEK293理论分子量 · 51.09 kDa

Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用

Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用