Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

Name: Anti-Tissue Factor Antibody (Tisotumab Biosimilar)
Brand: Puweituo Bio
SKU: TISSUEFACTOR-AB001

Catalog numberTISSUEFACTOR-AB001

HumanHEK293Molecular weight · 51.09 kDa

Product introduction

Anti-Tissue Factor Antibody (Tisotumab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target Tissue Factor, reactivity Human/Cynomolgus, isotype Human IgG1-Kappa, source-listed application ELISA.

Product details

Expression system: HEK293
Molecular weight: 51.09 kDa and 23.37 kDa.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: PBS, 10% glycerol (pH 7.4)
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Tisotumab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Tisotumab Biosimilar is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human Tissue Factor, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Tisotumab Biosimilar with the EC50 of 4.4ng/ml determined by ELISA. (QC Test)

Background

Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer.

References

1.Rao LV. Tissue factor as a tumor procoagulant. Cancer Metastasis Rev. 1992 Nov;11(3-4):249-66. doi: 10.1007/BF01307181. PMID: 1423817.
2.Carmeliet P, Collen D. Tissue factor. Int J Biochem Cell Biol. 1998 Jun;30(6):661-7. doi: 10.1016/s1357-2725(97)00121-0. PMID: 9695023.

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Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

Catalog numberTISSUEFACTOR-AB001

HumanHEK293Molecular weight · 51.09 kDa

Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References

Anti-Tissue Factor Antibody (Tisotumab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References