Biotinylated Human NaPi2b/SLC34A2 Nanodisc

Name: Biotinylated Human NaPi2b/SLC34A2 Nanodisc
Brand: 普维拓生物
SKU: SLC34A2-HB001

货号SLC34A2-HB001

HumanHEK293分子名 · NaPi-2b理论分子量 · 88.6 kDa

产品简介

Recombinant Biotinylated Human NaPi2b/SLC34A2 Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Leu689 (UniProt accession: O95436-2).

产品详情

分子别名: NaPi-2b; NaPi 2b; NAPI-IIb; NPTIIb; NaPi2b; PULAM;
蛋白长度: Met1-Leu689
表达系统: HEK293
理论分子量: The protein has a predicted MW of 88.6 kDa.
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
储存条件: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
阴性对照: CON-HM1NB

数据展示

ELISA Data — Immobilized Biotinylated Human NaPi2b Nanodisc, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Lifastuzumab, hFc Tag with the EC50 of 10.8ng/ml determined by ELISA. (QC Test)

SPR Data — Biotinylated Human NaPi2b Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Lifastuzumab, hFc Tag with an affinity constant of 2.64 nM as determined in SPR assay (Biacore T200).

背景介绍

SLC34A2, a member of the SLC34 family, is a multipass membrane protein and encodes a type 2b sodium-dependent phosphate transporter, NaPiIIb. It is known that SLC34A2 can mediate transporting inorganic phosphate into epithelial cells via sodium ion cotransport. SLC34A2 also strongly inhibited tumor growth and metastasis ability in an A549 subcutaneous tumor model and lung metastasis mode.

文献引用

1.Li Y, Chen X, Lu H. Knockdown of SLC34A2 Inhibits Hepatocellular Carcinoma Cell Proliferation and Invasion. Oncol Res. 2016 Oct 27;24(6):511-519. doi: 10.3727/096504016X14719078133483. PMID: 28281971; PMCID: PMC7838622.

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Biotinylated Human NaPi2b/SLC34A2 Nanodisc

产品简介

产品详情

数据展示

ELISA

ELISA Data

ELISA

ELISA Data

SPR

SPR Data

背景介绍

文献引用

Biotinylated Human NaPi2b/SLC34A2 Nanodisc

产品简介

产品详情

数据展示

ELISA

ELISA Data

ELISA

ELISA Data

SPR

SPR Data

背景介绍

文献引用