Biotinylated Rat MASP2 Protein (Primary Amine Labeling)

Name: Biotinylated Rat MASP2 Protein (Primary Amine Labeling)
Brand: 普维拓生物
SKU: MASP2-RB001

货号MASP2-RB001

RatE. coli分子名 · MAP19理论分子量 · 46.7 kDa

产品简介

Recombinant Biotinylated Rat MASP2 Protein (Primary Amine Labeling) is expressed in E. coli with a His tag at the C-terminus. It contains amino acid residues Thr287-Phe685 (accession: A2VCV7).

产品详情

分子别名: MAP19; MASP-2; MASP1P1; sMap;MASP2
蛋白长度: Thr287-Phe685
表达系统: E. coli
理论分子量: The protein has a predicted MW of 46.7 kDa. Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22μm filtered solution in 50mM Tris, 200mM NaCl (pH 9.0).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Biotinylated Rat MASP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

ELISA Data — Immobilized Narsoplimab, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Rat MASP2, His Tag with the EC50 of 19.3ng/ml determined by ELISA. (QC Test)

背景介绍

Te MASP2 gene is located on the chromosome 1p36.23–31 and encodes two proteins, MASP-2 and Map198. Both the levels and function of MASP-2 are modulated by the single-nucleotide polymorphisms (SNPs) of the MASP2 gene. Te level of MASP-2 in plasma plays a dual role in the infection and progression of infectious diseases. Te defciency of MASP-2 in plasma has been associated with the susceptibility of HIV. By contrast, the overproduction of MASP-2 may increase the infammatory efect.

文献引用

1.Li Z, Wang M, Zhong H, Huang X, Wu X, Zhang X, Wang J, Deng J, Chen M, Chen L, Tan H. Impact of MASP2 gene polymorphism and gene-tea drinking interaction on susceptibility to tuberculosis. Sci Rep. 2021 Mar 22;11(1):6544. doi: 10.1038/s41598-021-86129-x. PMID: 33753877; PMCID: PMC7985323.

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Biotinylated Rat MASP2 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用

Biotinylated Rat MASP2 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用