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Anti-MASP2 Antibody (Narsoplimab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target MASP2, reactivity Huma/Cynomolgus/Mouse/Rat, isotype Human IgG1-Kappa, source-listed application ELISA/SPR.
Te MASP2 gene is located on the chromosome 1p36.23–31 and encodes two proteins, MASP-2 and Map198. Both the levels and function of MASP-2 are modulated by the single-nucleotide polymorphisms (SNPs) of the MASP2 gene. Te level of MASP-2 in plasma plays a dual role in the infection and progression of infectious diseases. Te defciency of MASP-2 in plasma has been associated with the susceptibility of HIV. By contrast, the overproduction of MASP-2 may increase the infammatory efect.
