Biotinylated Human FcRL2/IRTA4 Protein (Primary Amine Labeling)

Name: Biotinylated Human FcRL2/IRTA4 Protein (Primary Amine Labeling)
Brand: 普维拓生物
SKU: IRTA4-HB001

货号IRTA4-HB001

HumanHEK293分子名 · FcR-like protein 2理论分子量 · 42.7 kDa

产品简介

Recombinant Biotinylated Human FcRL2/IRTA4 Protein (Primary Amine Labeling) is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Leu20-Val401 (UniProt accession: Q96LA5-1).

产品详情

分子别名: FcR-like protein 2; FcRL2; FCRH2; IFGP4; IRTA4; FCRL2; CD307b; FCRH2SPAP1B; IRTA4SPAP1C; SPAP1; SPAP1A
蛋白长度: Leu20-Val401
表达系统: HEK293
理论分子量: The protein has a predicted MW of 42.7 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Biotinylated Human FcRL2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

ELISA Data — Immobilized Biotinylated Human FcRL2, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-FcRL2 Antibody, hFc Tag with the EC50 of 28.2ng/ml determined by ELISA (QC Test).

背景介绍

Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation; P < 0.0001) and cells of other hematological diseases.

文献引用

1.Nückel H, Collins CH, Frey UH, Sellmann L, Dürig J, Siffert W, Dührsen U. FCRL2 mRNA expression is inversely associated with clinical progression in chronic lymphocytic leukemia. Eur J Haematol. 2009 Dec 1;83(6):541-9. doi: 10.1111/j.1600-0609.2009.01328.x. Epub 2009 Aug 4. PMID: 19682311.

加载中…

Biotinylated Human FcRL2/IRTA4 Protein (Primary Amine Labeling)

货号IRTA4-HB001

HumanHEK293分子名 · FcR-like protein 2理论分子量 · 42.7 kDa

Biotinylated Human FcRL2/IRTA4 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用

Biotinylated Human FcRL2/IRTA4 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用