Human FGF10 Protein

Name: Human FGF10 Protein
Brand: 普维拓生物
SKU: FGF10-HP001

货号FGF10-HP001

HumanE. coli分子名 · FGF-10; KGF2理论分子量 · 19.3 kDa

产品简介

Recombinant Human FGF10 Protein is expressed in E. coli without tag. It contains amino acid residues Gln38-Ser208 (UniProt accession: O15520).

产品详情

分子别名: FGF-10; KGF2
蛋白长度: Gln38-Ser208
表达系统: E. coli
理论分子量: The protein has a predicted MW of 19.3 kDa. The protein migrates to 25 kDa based on Bis-Tris PAGE result.
纯度: > 90% as determined by Bis-Tris PAGE
内毒素: Less than 0.1 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22μm filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Human FGF10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SPR Data — Human FGF10, No Tag immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb), hFc Tag with an affinity constant of 8.43 nM as determined in SPR assay (Biacore T200).

背景介绍

Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.

文献引用

1.Prince LS. FGF10 and Human Lung Disease Across the Life Spectrum. Front Genet. 2018 Oct 31;9:517. doi: 10.3389/fgene.2018.00517. PMID: 30429870; PMCID: PMC6220039.

加载中…

Human FGF10 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SPR

SPR Data

背景介绍

文献引用

Human FGF10 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SPR

SPR Data

背景介绍

文献引用