Biotinylated Human CX3CR1 Nanodisc

Name: Biotinylated Human CX3CR1 Nanodisc
Brand: 普维拓生物
SKU: CX3CR1-HB002

货号CX3CR1-HB002

HumanHEK293分子名 · CX3C chemokine receptor 1理论分子量 · 53.40 kDa

产品简介

Recombinant Biotinylated Human CX3CR1 Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Leu355 (UniProt accession: P49238-1).

产品详情

分子别名: CX3C chemokine receptor 1; C-X3-C CKR-1; CMK-BRL-1; CMK-BRL1; V28; CMKBRL1; GPR13; GPRV28; C-X3C CKR1
蛋白长度: Met1-Leu355
表达系统: HEK293
理论分子量: The protein has a predicted MW of 53.40 kDa.
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
储存条件: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
阴性对照: CON-HM1NB

数据展示

ELISA Data — Immobilized Biotinylated Human CX3CR1 Nanodisc, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-CX3CR1 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. (QC Test)

背景介绍

CX3CR1, also known as G-protein coupled receptor 13, is a receptor of CX3CL1. It is primarily expressed on monocytes, macrophages, dendritic cells, T cells, and natural killer cells. The binding of CX3CL1 to CX3CR1 induces the activation of heterotrimeric G proteins associated with this receptor. In addition, it triggers the signal pathways of MAPK and AKT, which play essential roles in tumour biology.

文献引用

1.Lu X. Structure and Function of Ligand CX3CL1 and its Receptor CX3CR1 in Cancer. Curr Med Chem. 2022;29(41):6228-6246. doi: 10.2174/0929867329666220629140540. PMID: 35770395.

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Biotinylated Human CX3CR1 Nanodisc

产品简介

产品详情

数据展示

ELISA

ELISA Data

背景介绍

文献引用

Biotinylated Human CX3CR1 Nanodisc

产品简介

产品详情

数据展示

ELISA

ELISA Data

背景介绍

文献引用