Biotinylated Human CX3CR1 Nanodisc

Name: Biotinylated Human CX3CR1 Nanodisc
Brand: Puweituo Bio
SKU: CX3CR1-HB002

Catalog numberCX3CR1-HB002

HumanHEK293Molecule · CX3C chemokine receptor 1Molecular weight · 53.40 kDa

Product introduction

Recombinant Biotinylated Human CX3CR1 Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Leu355 (UniProt accession: P49238-1).

Product details

Molecular aliases: CX3C chemokine receptor 1; C-X3-C CKR-1; CMK-BRL-1; CMK-BRL1; V28; CMKBRL1; GPR13; GPRV28; C-X3C CKR1
Protein length: Met1-Leu355
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 53.40 kDa.
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Storage: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Negative control: CON-HM1NB

Data display

ELISA Data — Immobilized Biotinylated Human CX3CR1 Nanodisc, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-CX3CR1 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. (QC Test)

Background

CX3CR1, also known as G-protein coupled receptor 13, is a receptor of CX3CL1. It is primarily expressed on monocytes, macrophages, dendritic cells, T cells, and natural killer cells. The binding of CX3CL1 to CX3CR1 induces the activation of heterotrimeric G proteins associated with this receptor. In addition, it triggers the signal pathways of MAPK and AKT, which play essential roles in tumour biology.

References

1.Lu X. Structure and Function of Ligand CX3CL1 and its Receptor CX3CR1 in Cancer. Curr Med Chem. 2022;29(41):6228-6246. doi: 10.2174/0929867329666220629140540. PMID: 35770395.

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Biotinylated Human CX3CR1 Nanodisc

Catalog numberCX3CR1-HB002

HumanHEK293Molecule · CX3C chemokine receptor 1Molecular weight · 53.40 kDa

Product introduction

Recombinant Biotinylated Human CX3CR1 Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Leu355 (UniProt accession: P49238-1).

Biotinylated Human CX3CR1 Nanodisc

Product introduction

Product details

Data display

ELISA

ELISA Data

Background

References

Biotinylated Human CX3CR1 Nanodisc

Product introduction

Product details

Data display

ELISA

ELISA Data

Background

References