Biotinylated Human Claudin 18.2 VLP Protein

Name: Biotinylated Human Claudin 18.2 VLP Protein
Brand: 普维拓生物
SKU: CLDN182-HB001

货号CLDN182-HB001

HEK293分子名 · CLDN18理论分子量 · 29 kDa

产品简介

Biotinylated Human Claudin 18.2 VLP Protein is a full-length multi-pass membrane protein displayed in a VLP format for antibody discovery, binding assays and method development. The construct is expressed in HEK293 cells and contains Met1-Val261 (UniProt accession: P56856-2).

产品详情

分子别名: CLDN18; CLDN18.2; Claudin-18.2; Claudin18.2; Claudin-18; DKFZp564B2062; SFTA5; SFTPJ
蛋白长度: Met1-Val261
表达系统: HEK293
理论分子量: 29 kDa
纯度: >95% (HPLC)
内毒素: <1 EU/μg (LAL assay)
缓冲液 / 制剂: 0.22 μm filtered solution in PBS with 300 mM L-arginine, pH 7.4.
储存条件: Store at -80°C for up to 12 months. Aliquot where appropriate and minimize freeze-thaw cycles.
阴性对照: GPR-HM05CB

背景介绍

Claudin-18 (CLDN18) is a member of the claudin family that forms tight-junction strands in epithelial cells. CLDN18 is expressed in stomach and lung tissues and has two splice variants, CLDN18.1 and CLDN18.2. Claudin-18.2 is enriched in gastric tumors.

文献引用

1.Singh P, Toom S, Huang Y. Anti-claudin 18.2 antibody as new targeted therapy for advanced gastric cancer. J Hematol Oncol. 2017;10(1):105.

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