Human CCR8 VLP Protein

Name: Human CCR8 VLP Protein
Brand: 普维拓生物
SKU: CCR8-HP001

货号CCR8-HP001

HumanHEK293分子名 · CCR-8理论分子量 · 44.06 kDa

产品简介

Human CCR8 VLP Protein is a full-length multi-pass membrane protein displayed in a VLP format for antibody discovery, binding assays and method development. The construct is expressed in HEK293 cells and contains the indicated native protein sequence.

产品详情

分子别名: CCR-8; CMKBRL2; CKR-L1; GPR-CY6; TER1; CCR8; CKRL1; CMKBR8; CD198; ChemR1; CY6; TER-1; CDw198
蛋白长度: Met1-Leu355
表达系统: HEK293
理论分子量: 44.06 kDa
纯度: >95% (HPLC)
内毒素: <1 EU/μg (LAL assay)
缓冲液 / 制剂: 0.22 μm filtered solution in PBS with 300 mM L-arginine, pH 7.4. A water-soluble adjuvant is recommended for immunization applications.
储存条件: Store at -80°C for up to 12 months. Aliquot where appropriate and minimize freeze-thaw cycles.
阴性对照: STP-HM0VC

背景介绍

CCR8 (CD198) is a CC chemokine receptor expressed on cell populations including Th2 cells and eosinophils. It has been studied in allergic inflammation, monocyte chemotaxis and thymic cell biology, and can act as an alternative HIV-1 coreceptor with CD4.

文献引用

1.Berenguer J, Lagerweij T, Zhao XW, et al. Glycosylated extracellular vesicles released by glioblastoma cells are decorated by CCL18 allowing for cellular uptake via chemokine receptor CCR8. J Extracell Vesicles. 2018;7(1):1446660.

加载中…