Human APLNR VLP Protein

Name: Human APLNR VLP Protein
Brand: 普维拓生物
SKU: APLNR-HP001

货号APLNR-HP001

HEK293分子名 · Apelin receptor理论分子量 · 46.7 kDa

产品简介

Recombinant Human APLNR VLP protein is expressed in HEK293 cells and contains Met1-Asp380 (UniProt accession: P35414). The full-length receptor is displayed in a virus-like particle format for antibody-binding, immunization and assay-development research.

产品详情

分子别名: Apelin receptor; AGTRL1; APJ; HG11; APJR; AR
蛋白长度: Met1-Asp380
表达系统: HEK293
理论分子量: 46.7 kDa
纯度: >95% (HPLC)
内毒素: <1 EU/μg (LAL assay)
缓冲液 / 制剂: PBS with 200 mM L-arginine, pH 7.4.
储存条件: Store at -80°C for up to 12 months. Minimize freeze-thaw cycles.

背景介绍

The apelin receptor (APJ) is a class A G protein-coupled receptor involved in the regulation of cardiovascular and central nervous system functions. APJ signaling has been studied in hypertension, atherosclerosis and cerebral stroke, making the receptor a research target in cardiovascular and neurological disease biology.

文献引用

1.Hu S, Wang D, Liu W, Wang Y, Chen J, Cai X. Apelin receptor dimer: Classification, future prospects, and pathophysiological perspectives. Biochim Biophys Acta Mol Basis Dis. 2024 Aug;1870(6):167257. doi: 10.1016/j.bbadis.2024.167257. PMID: 38795836.

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