Human APLNR VLP Protein

Name: Human APLNR VLP Protein
Brand: Puweituo Bio
SKU: APLNR-HP001

Catalog numberAPLNR-HP001

HEK293Molecule · Apelin receptorMolecular weight · 46.7 kDa

Product introduction

Recombinant Human APLNR VLP protein is expressed in HEK293 cells and contains Met1-Asp380 (UniProt accession: P35414). The full-length receptor is displayed in a virus-like particle format for antibody-binding, immunization and assay-development research.

Product details

Molecular aliases: Apelin receptor; AGTRL1; APJ; HG11; APJR; AR
Protein length: Met1-Asp380
Expression system: HEK293
Molecular weight: 46.7 kDa
Purity: >95% (HPLC)
Endotoxin: <1 EU/μg (LAL assay)
Formulation: PBS with 200 mM L-arginine, pH 7.4.
Storage: Store at -80°C for up to 12 months. Minimize freeze-thaw cycles.

Background

The apelin receptor (APJ) is a class A G protein-coupled receptor involved in the regulation of cardiovascular and central nervous system functions. APJ signaling has been studied in hypertension, atherosclerosis and cerebral stroke, making the receptor a research target in cardiovascular and neurological disease biology.

References

1.Hu S, Wang D, Liu W, Wang Y, Chen J, Cai X. Apelin receptor dimer: Classification, future prospects, and pathophysiological perspectives. Biochim Biophys Acta Mol Basis Dis. 2024 Aug;1870(6):167257. doi: 10.1016/j.bbadis.2024.167257. PMID: 38795836.

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