Pattern recognition and initial sensing
Identify pathogen- and damage-associated signals through surface and intracellular pattern-recognition receptors.
Explore pathwayTLR / RLR / NLRPAMP / DAMP
Innate immunity and complement research
Explore pathogen sensing, myeloid-cell regulation, inflammatory mediators and complement cascades for mechanism studies and target evaluation.
- Innate immunity and complement pathways
- Receptors, ligands and regulators
- Recombinant and labelled protein tools
Key innate-immunity research pathways
Myeloid and phagocytic regulation
Study phagocytic recognition and immune regulation in macrophages, monocytes and dendritic cells.
Explore pathwayCD47–SIRPαCD33 · M-CSF
Inflammatory mediators and innate output
Connect cytokine release and inflammatory amplification with downstream innate-immune experiments.
Explore pathwayIL-1α · IL-6IL-18 · IL-33
Complement activation, convergence and effect
Classical pathway
Antibodies and immune complexes
C1 · C4 · C2
Lectin pathway
Glycan pattern recognition
MBL · Ficolin · MASP
Alternative pathway
Microbial and altered surfaces
Factor B · Factor D · Properdin
C3 / C5 convergence hub
C1 inhibitor · CR1 / CD35 · Factor H / Factor I · CD46 / CD55
Inflammatory amplification
C3a and C5a support inflammatory-cell recruitment and signal amplification.
Opsonization and phagocytosis
C3b marks target surfaces for immune-cell recognition and clearance.
Membrane attack complex
C5b–C9 forms an effector pore on the membrane surface.
Product and quality information
Review available information before selecting a product.
Key specifications
Activity information
Quality documents
Application notes