Human TM4SF1 Nanodisc Protein

Name: Human TM4SF1 Nanodisc Protein
Brand: 普维拓生物
SKU: TM4SF1-HP002

货号TM4SF1-HP002

HumanHEK293分子名 · M3S1; TAAL6; H-L6; L6

产品简介

Human TM4SF1 Nanodisc Protein is a full-length multi-pass membrane protein presented in a Nanodisc format for antibody discovery, binding assays and method development. Recombinant Human TM4SF1 Nanodisc is expressed from HEK293 with His tag at the N-terminus (FITC-equivalent protein is fused on cytoplasmic part). It contains Met1-Cys202 (accession: P30408).

产品详情

分子别名: M3S1; TAAL6; H-L6; L6
蛋白长度: Met1-Cys202
表达系统: HEK293
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.

背景介绍

Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.

文献引用

1.Yang JC, Zhang Y, He SJ, Li MM, Cai XL, Wang H, Xu LM, Cao J. TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. Sci Rep. 2017 Apr 3;7:45895. doi: 10.1038/srep45895. PMID: 28368050; PMCID: PMC5377454.

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