Biotinylated Human SLC6A17 Nanodisc

Name: Biotinylated Human SLC6A17 Nanodisc
Brand: 普维拓生物
SKU: SLC6A17-HB001

货号SLC6A17-HB001

HumanHEK293分子名 · NTT4; MRT48理论分子量 · 94.0 kDa

产品简介

Recombinant Biotinylated Human SLC6A17 Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Leu727 (UniProt accession: Q9H1V8).

产品详情

分子别名: NTT4; MRT48
蛋白长度: Met1-Leu727
表达系统: HEK293
理论分子量: The protein has a predicted MW of 94.0 kDa.
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
储存条件: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
阴性对照: CON-HM1NB

数据展示

ELISA Data — Immobilized Biotinylated Human SLC6A17 Nanodisc, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-SLC6A17 Antibody, Rabbit Fc Tag with the EC50 of 2.0ng/ml determined by ELISA. (QC Test)

SPR Data — Biotinylated Human SLC6A17 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-SLC6A17 Antibody, Rabbit Fc Tag with an affinity constant of 0.39 nM as determined in SPR assay (Biacore T200).

背景介绍

The vesicular B0AT3 transporter (SLC6A17) one of the members of the SLC6 family, is predominantly expressed in the brain, encodes a synaptic vesicular transporter of neutral amino acids and glutamate, and plays an important role in the regulation of glutamatergic synapses.

文献引用

1.Iqbal Z, Willemsen MH, Papon MA, Musante L, Benevento M, Hu H, Venselaar H, Wissink-Lindhout WM, Vulto-van Silfhout AT, Vissers LE, de Brouwer AP, Marouillat S, Wienker TF, Ropers HH, Kahrizi K, Nadif Kasri N, Najmabadi H, Laumonnier F, Kleefstra T, van Bokhoven H. Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems. Am J Hum Genet. 2015 Mar 5;96(3):386-96. doi: 10.1016/j.ajhg.2015.01.010. Epub 2015 Feb 19. PMID: 25704603; PMCID: PMC4375531.

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Biotinylated Human SLC6A17 Nanodisc

产品简介

产品详情

数据展示

ELISA

ELISA Data

SPR

SPR Data

背景介绍

文献引用

Biotinylated Human SLC6A17 Nanodisc

产品简介

产品详情

数据展示

ELISA

ELISA Data

SPR

SPR Data

背景介绍

文献引用