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Recombinant Biotinylated Human RGM-C Protein is expressed in HEK293 cells with an Avi tag at the C-terminus. It contains amino acid residues Gln36-Asp400 (UniProt accession: Q6ZVN8-1).
RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C),both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system.
