Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein

Name: Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein
Brand: 普维拓生物
SKU: QA1B-HB001

货号QA1B-HB001

MouseHEK293分子名 · Qdm; Qa-1b; MHC; H2-T23理论分子量 · 50.60 kDa

产品简介

Recombinant Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains His23-Pro296(Qa-1b), Ile21-Met119(B2M) and AMAPRTLLL peptide (accession: P06339(Q1-1b) & P01887(B2M) &AMAPRTLLL).

产品详情

分子别名: Qdm; Qa-1b; MHC; H2-T23
蛋白长度: His23-Pro296
表达系统: HEK293
理论分子量: The protein has a predicted MW of 50.60 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer is greater than 95% as determined by SEC-HPLC.

背景介绍

Qa-1b binds a peptide (AMAPRTLLL), referred to as Qdm (for Qa-1 determinant modifier), derived from the signal sequence of murine class Ia molecules. This peptide binds with high affinity and accounts for almost all of the peptides associated with this molecule. Human histocompatibility leukocyte antigen (HLA)-E, a homologue of Qa-1b, binds similar peptides derived from human class Ia molecules and interacts with CD94/NKG2 receptors on natural killer cells.

文献引用

1.Kurepa Z, Hasemann CA, Forman J. Qa-1b binds conserved class I leader peptides derived from several mammalian species. J Exp Med. 1998 Sep 7;188(5):973-8. doi: 10.1084/jem.188.5.973. PMID: 9730898; PMCID: PMC2213384.

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Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein

货号QA1B-HB001

MouseHEK293分子名 · Qdm; Qa-1b; MHC; H2-T23理论分子量 · 50.60 kDa

Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

背景介绍

文献引用

Biotinylated Mouse Qa-1b&B2M&Qdm (AMAPRTLLL) Monomer Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

背景介绍

文献引用