PE-Labeled Human PD-1/PDCD1 Protein

Name: PE-Labeled Human PD-1/PDCD1 Protein
Brand: 普维拓生物
SKU: PD1-HP003

货号PD1-HP003

HumanHEK293分子名 · PDCD1理论分子量 · 17 kDa

产品简介

Recombinant PE-Labeled Human PD-1/PDCD1 Protein is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Leu25-Gln167 (UniProt accession: Q15116).

产品详情

分子别名: PDCD1; PD1; CD279; SLEB2; PD-1
蛋白长度: Leu25-Gln167
表达系统: HEK293
理论分子量: The protein has a predicted MW of 17 kDa.
缓冲液 / 制剂: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
储存条件: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

背景介绍

Programmed cell death protein 1, also known as PD-1 and CD279, is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.

文献引用

1.Blank C, Mackensen A. Contribution of the PD-L1/PD-1 pathway to T-cell exhaustion: an update on implications for chronic infections and tumor evasion[J]. Cancer Immunology Immunotherapy, 2007, 56(5):739-745.

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