Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)

Name: Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)
Brand: 普维拓生物
SKU: PADI4-CB001

货号PADI4-CB001

E. coli分子名 · Protein-arginine deiminase type-4理论分子量 · 76.6 kDa

产品简介

Recombinant Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) is expressed in E. coli with a His tag at the N-terminus. It contains amino acid residues Met1-Pro663 (UniProt accession: A0A2K5USI5).

产品详情

分子别名: Protein-arginine deiminase type-4; HL-60 PAD; HL60 PAD; HL-60; PAD; PAD4; PADI5; PDI5; HL60PAD; HL60
蛋白长度: Met1-Pro663
表达系统: E. coli
理论分子量: The protein has a predicted MW of 76.6 kDa same as Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22μm filtered solution in 20mM Tris, 500mM NaCl, 10% Glycerol, 0.5mM TCEP, 1mM EDTA (pH 8.0).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Biotinylated Cynomolgus PADI4 (Primary Amine Labeling) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

ELISA Data — Immobilized Biotinylated Cynomolgus PADI4, His Tag at 1μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-PADI4 Antibody, hFc Tag with the EC50 of 7.2ng/ml determined by ELISA. (QC Test)

背景介绍

Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.

文献引用

1.Seri Y, Shoda H, Matsumoto I, Sumida T, Fujio K, Yamamoto K. [Peptidylarginine deiminase type4 (PADI4) role in immune system]. Nihon Rinsho Meneki Gakkai Kaishi. 2014;37(3):154-9. Japanese. doi: 10.2177/jsci.37.154. PMID: 24974927.

加载中…

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)

货号PADI4-CB001

E. coli分子名 · Protein-arginine deiminase type-4理论分子量 · 76.6 kDa

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用

Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用