Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein

Name: Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein
Brand: 普维拓生物
SKU: HLAA0201-HP007

货号HLAA0201-HP007

HumanE. coli分子名 · KMQGAPPAV; MTMR5理论分子量 · 35.6 kDa

产品简介

Recombinant Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KMQGAPPAV peptide (accession: A0A140T913(HLA-A*02:01) & P61769(B2M) &KMQGAPPAV).

产品详情

分子别名: KMQGAPPAV; MTMR5
蛋白长度: Gly25-Thr305
表达系统: E. coli
理论分子量: The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in 20 mM Tris, 200 mM NaCl (pH 8.0).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-B2M Antibody, mFc Tag with the EC50 of 9.0ng/ml determined by ELISA (QC Test).

背景介绍

The human SBF1 (SET binding factor 1) gene, alternatively known as MTMR5, is predominantly expressed in the brain, and its epigenetic dysregulation is linked to late-onset neurocognitive disorders (NCDs), such as Alzheimer's disease.

文献引用

1.Khamse S, Alizadeh S, Bernhart SH, Afshar H, Delbari A, Ohadi M. A (GCC) repeat in SBF1 reveals a novel biological phenomenon in human and links to late onset neurocognitive disorder. Sci Rep. 2022 Sep 14;12(1):15480. doi: 10.1038/s41598-022-19878-y. PMID: 36104480; PMCID: PMC9474449.

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Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein

货号HLAA0201-HP007

HumanE. coli分子名 · KMQGAPPAV; MTMR5理论分子量 · 35.6 kDa

Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用

Human HLA-A*02:01&B2M&MTMR5 (KMQGAPPAV) Monomer Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用