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Recombinant Human FGF-7/KGF Protein is expressed in E. coli with a His tag at the N-terminus. It contains amino acid residues Cys32-Thr194 (UniProt accession: P21781-1).
The expression patterns of mRNAs encoding Fibroblast Growth Factor-7 (FGF-7) and its high affinity receptor suggested that FGF-7 signaling may play a role in regulating ureteric bud growth.t Results of these studies demonstrate that the developing ureteric bud and mature collecting system of FGF-7-null kidneys is markedly smaller than wild type. FGF-7 levels modulate the extent of ureteric bud growth during development and the number of nephrons that eventually form in the kidney.
