Biotinylated Human DLL3 Domain (352-479) Protein

Name: Biotinylated Human DLL3 Domain (352-479) Protein
Brand: 普维拓生物
SKU: DLL3-HB004

货号DLL3-HB004

HumanHEK293分子名 · Delta3理论分子量 · 17.30 kDa

产品简介

Recombinant Biotinylated Human DLL3 Domain (352-479) Protein is expressed in HEK293 cells with a His tag and Avi tag at the C-terminus. It contains amino acid residues Lys352-Ala479 (UniProt accession: Q9NYJ7-1).

产品详情

分子别名: Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3
蛋白长度: Lys352-Ala479
表达系统: HEK293
理论分子量: The protein has a predicted MW of 17.30 kDa. Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS, 100mM L-arginine (pH 7.4).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Biotinylated Human DLL3 Domain (352-479) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

背景介绍

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).

文献引用

1.Saunders L R, Bankovich A J, Anderson W C, et al. A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo[J]. Science Translational Medicine, 2015.

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Biotinylated Human DLL3 Domain (352-479) Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

背景介绍

文献引用

Biotinylated Human DLL3 Domain (352-479) Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

背景介绍

文献引用