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Recombinant Human CCL20 Protein is expressed in E. coli with a His tag at the N-terminus. It contains amino acid residues Ala27-Met96 (UniProt accession: P78556-1).
Recent evidence suggests that CC chemokine ligand 20 (CCL20) is upregulated after subarachnoid hemorrhage (SAH). CCL20 is upregulated in an SAH mouse model and in cultured primary microglia and neurons. CCL20-neutralizing antibody alleviated SAH-induced neurological deficits, decreased brain water content and neuronal apoptosis, and repressed microglial activation.
