Mouse BTLA Protein

Name: Mouse BTLA Protein
Brand: 普维拓生物
SKU: BTLA-MP001

货号BTLA-MP001

MouseHEK293分子名 · CD272理论分子量 · 17.8 kDa

产品简介

Recombinant Mouse BTLA Protein is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Glu30-Gly176 (UniProt accession: Q32MV9).

产品详情

分子别名: CD272; BTLA; BTLA1; FLJ16065; MGC129743
蛋白长度: Glu30-Gly176
表达系统: HEK293
理论分子量: The protein has a predicted MW of 17.8 kDa. Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
内毒素: Less than 0.1 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Mouse BTLA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Mouse BTLA is greater than 95% as determined by SEC-HPLC.

背景介绍

B- and T-lymphocyte attenuator (BTLA; CD272) is a 35 kDa type I transmembrane glycoprotein in the CD28 family of T cell costimulatory molecules. BTLA is a inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2. BTLA may interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14.

文献引用

1.Haymaker C L, Wu R C, Ritthipichai K, et al. BTLA marks a less-differentiated tumor-infiltrating lymphocyte subset in melanoma with enhanced survival properties[J]. OncoImmunology, 2015, 4(8):e1014246. Note: HPLC results always come from liquid protein, due to absorption peak interference of trehalose in lyophilized powder.

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Mouse BTLA Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

背景介绍

文献引用

Mouse BTLA Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

背景介绍

文献引用