Biotinylated Human APOE3/Apolipoprotein E Protein

Name: Biotinylated Human APOE3/Apolipoprotein E Protein
Brand: 普维拓生物
SKU: APOE3-HB001

货号APOE3-HB001

HumanHEK293分子名 · Apolipoprotein E理论分子量 · 37.66 kDa

产品简介

Recombinant Biotinylated Human APOE3/Apolipoprotein E Protein is expressed in HEK293 cells with a His tag and Avi tag at the C-terminus. It contains amino acid residues Lys19-His317 (UniProt accession: P02649-1).

产品详情

分子别名: Apolipoprotein E; Apo-E; APOE; apolipo E; APOE3
蛋白长度: Lys19-His317
表达系统: HEK293
理论分子量: The protein has a predicted MW of 37.66 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

数据展示

Bis-Tris PAGE Data — Biotinylated Human APOE3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

背景介绍

Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD).

文献引用

1.Zhao N, Liu CC, Qiao W, Bu G. Apolipoprotein E, Receptors, and Modulation of Alzheimer's Disease. Biol Psychiatry. 2018 Feb 15;83(4):347-357. doi: 10.1016/j.biopsych.2017.03.003. Epub 2017 Mar
2.PMID: 28434655; PMCID: PMC5599322.

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Biotinylated Human APOE3/Apolipoprotein E Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

背景介绍

文献引用

Biotinylated Human APOE3/Apolipoprotein E Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

背景介绍

文献引用