Mouse 4-1BB/TNFRSF9 Protein

Name: Mouse 4-1BB/TNFRSF9 Protein
Brand: 普维拓生物
SKU: 41BB-MP001

货号41BB-MP001

MouseHEK293分子名 · CD137理论分子量 · 21.2 kDa

产品简介

Recombinant Mouse 4-1BB/TNFRSF9 Protein is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Val24-Leu211 (accession: NP_001070976.1).

产品详情

分子别名: CD137; TNFRSF9; 4-1BB ligand receptor; 41BB; 4-1BB; CDw137; FLJ43501; ILA; T cell antigen ILA
蛋白长度: Val24-Leu211
表达系统: HEK293
理论分子量: The protein has a predicted MW of 21.2 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE
内毒素: Less than 0.1 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Mouse 4-1BB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

ELISA Data — Immobilized Mouse 4-1BB, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Mouse 4-1BB Ligand, hFc Tag with the EC50 of 2.4ng/ml determined by ELISA. (QC Test)

背景介绍

4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation.

文献引用

1.Vinay D S, Kwon B S. 4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy[J]. BMB Reports, 2014, 47(3):122-129.

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Mouse 4-1BB/TNFRSF9 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用

Mouse 4-1BB/TNFRSF9 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

ELISA

ELISA Data

背景介绍

文献引用