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Recombinant Marmoset TNFSF15 Protein is expressed in HEK293 cells with a His tag at the N-terminus. It contains amino acid residues Ser57-Leu251 (accession: F7HVJ8).
TNF superfamily member 15 (TNFSF15), a cytokine largely produced by vascular endothelial cells and a specific inhibitor of the proliferation of these same cells, can inhibit VEGF-induced vascular permeability in vitro and in vivo, and that death receptor 3 (DR3), a cell surface receptor of TNFSF15, mediates TNFSF15-induced dephosphorylation of VEGFR2.
