Biotinylated Human STEAP1 VLP

Name: Biotinylated Human STEAP1 VLP
Brand: 普维拓生物
SKU: STEAP1-HB002

货号STEAP1-HB002

HumanHEK293分子名 · PRSS24理论分子量 · 43.06 kDa

产品简介

Recombinant Biotinylated Human STEAP1 VLP is expressed in HEK293 cells. It contains amino acid residues Met1-Leu339 (It may have cross reaction with anti-His antibody) (UniProt accession: Q9UHE8).

产品详情

分子别名: PRSS24; STEAP; PRSS24, STEAP 1;PRSS24, STEAP1
蛋白长度: Met1-Leu339
表达系统: HEK293
理论分子量: The protein has a predicted MW of 43.06 kDa.
纯度: > 95% as determined by HPLC
缓冲液 / 制剂: Supplied as 0.22 μm filtered solution in PBS, 300mM L-arginine (pH 7.4).
储存条件: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
阴性对照: CON-HM00VB

数据展示

SEC-HPLC Data — The purity of Biotinylated Human STEAP1 VLP is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Biotinylated Human STEAP1 VLP at 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Vandortuzumab, hFc Tag with the EC50 of 91.2ng/ml determined by ELISA. (QC Test)

背景介绍

Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several human cancers, making it a promising therapeutic target to manage these diseases. It shares sequence homology with three enzymes (STEAP2-STEAP4) that catalyze the NADPH-dependent reduction of iron(III).

文献引用

1.Oosterheert W, Gros P. Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1). J Biol Chem. 2020 Jul 10;295(28):9502-9512. doi: 10.1074/jbc.RA120.013690. Epub 2020 May 14. PMID: 32409586; PMCID: PMC7363144.

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Biotinylated Human STEAP1 VLP

产品简介

产品详情

数据展示

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用

Biotinylated Human STEAP1 VLP

产品简介

产品详情

数据展示

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用