Mouse M-CSF/CSF-1 Protein

Name: Mouse M-CSF/CSF-1 Protein
Brand: 普维拓生物
SKU: MCSF-MP001

货号MCSF-MP001

MouseHEK293分子名 · CSF1理论分子量 · 25.98 kDa

产品简介

Recombinant Mouse M-CSF/CSF-1 Protein is expressed in HEK293 cells without tag. It contains amino acid residues Lys33-Glu262 (UniProt accession: P07141-1).

产品详情

分子别名: CSF1; CSF-1; MCSF; M-CSF; MGC31930; Lanimostim; Colony stimulating factor-1; Colony stimulating factor 1
蛋白长度: Lys33-Glu262
表达系统: HEK293
理论分子量: The protein has a predicted MW of 25.98 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Mouse M-CSF on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Mouse M-CSF is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Mouse M-CSF, No Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Mouse M-CSF R, His Tag with the EC50 of 1.69μg/ml determined by ELISA (QC Test).

背景介绍

CSF-1, also known as M-CSF, is a four alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. CSF-1 is also essential for the survival and proliferation of osteoclast progenitors. CSF-1 is cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes.

文献引用

1.Cannarile M A, Weisser M, Jacob W, et al. Colony-stimulating factor 1 receptor (CSF1R) inhibitors in cancer therapy[J]. Journal for ImmunoTherapy of Cancer, 2017, 5(1):53.

加载中…

Mouse M-CSF/CSF-1 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用

Mouse M-CSF/CSF-1 Protein

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用