Biotinylated Human FcRH5/FcRL5 Protein (Primary Amine Labeling)

Name: Biotinylated Human FcRH5/FcRL5 Protein (Primary Amine Labeling)
Brand: 普维拓生物
SKU: FCRH5FCRL5-HB001

货号FCRH5FCRL5-HB001

HumanHEK293分子名 · FcR-like protein 5理论分子量 · 92.38 kDa

产品简介

Recombinant Biotinylated Human FcRH5/FcRL5 Protein (Primary Amine Labeling) is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Gln16-Gly851 (UniProt accession: Q96RD9-1).

产品详情

分子别名: FcR-like protein 5; FcRH5; FcRL5; BXMAS1; BXMAS1MGC119592; CD307; CD307e; DKFZp667E2019; DKFZp667F216; FCRH5MGC119593; FLJ00333; FLJ00397; IFGP5; IRTA2
蛋白长度: Gln16-Gly851
表达系统: HEK293
理论分子量: The protein has a predicted MW of 92.38 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result.
纯度: > 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC
内毒素: Less than 1 EU per μg by the LAL method.
缓冲液 / 制剂: Lyophilized from 0.22μm filtered solution in PBS, 100mM Arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
状态: 冻干粉
储存条件: -20 to -80°C for 12 months as supplied from date of receipt. -80°C for 3 months after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
复溶建议: Dissolve the lyophilized protein in distilled water. Please refer to the Certificate of Analysis for detailed instructions.

数据展示

Bis-Tris PAGE Data — Biotinylated Human FcRH5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Biotinylated Human FcRH5 is greater than 90% as determined by SEC-HPLC.

ELISA Data — Immobilized Anti-FcRH5 Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human FcRH5, His Tag with the EC50 of 35.6ng/ml determined by ELISA (QC Test).

背景介绍

FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.

文献引用

1.Elkins K, Zheng B, Go M, et al. FcRL5 as a target of antibody-drug conjugates for the treatment of multiple myeloma. Mol Cancer Ther. 2012;11(10):2222-2232. doi:10.1158/1535-7163. MCT-12-0087.

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Biotinylated Human FcRH5/FcRL5 Protein (Primary Amine Labeling)

货号FCRH5FCRL5-HB001

HumanHEK293分子名 · FcR-like protein 5理论分子量 · 92.38 kDa

Biotinylated Human FcRH5/FcRL5 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用

Biotinylated Human FcRH5/FcRL5 Protein (Primary Amine Labeling)

产品简介

产品详情

数据展示

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

背景介绍

文献引用