Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)

Name: Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)
Brand: Puweituo Bio
SKU: VEGFR2-AB001

Catalog numberVEGFR2-AB001

HumanHEK293Molecular weight · 52.0 kDa

Product introduction

Anti-VEGF R2 Antibody (Ramucirumab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target VEGF R2, reactivity Human/Rhesus macaque, isotype Human IgG1-Kappa, source-listed application ELISA.

Product details

Expression system: HEK293
Molecular weight: 52.0 kDa and 23.3 kDa.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: PBS, 10% glycerol (pH 7.4)
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Ramucirumab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Ramucirumab Biosimilar is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human VEGF R2, His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Ramucirumab Biosimilar with the EC50 of 5.5/5.2ng/ml determined by ELISA. (QC Test)

Background

The vascular endothelial growth factor receptor-2 (VEGFR-2/KDR/flk-1) functions as the primary mediator of vascular endothelial growth factor activation in endothelial cells. Regulation of VEGFR-2 expression appears critical in mitogenesis, differentiation, and angiogenesis. Transcriptional regulation of the VEGFR-2 is complex and may involve multiple putative upstream regulatory elements including E boxes.

References

1.PMID: 15941713.

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Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References

Anti-VEGF R2 Antibody (Ramucirumab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References