Anti-TSLP Antibody (Tezepelumab Biosimilar)

Name: Anti-TSLP Antibody (Tezepelumab Biosimilar)
Brand: Puweituo Bio
SKU: TSLP-AB001

Catalog numberTSLP-AB001

HumanHEK293Molecular weight · 49.5 kDa

Product introduction

Anti-TSLP Antibody (Tezepelumab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target TSLP, reactivity Human/Cynomolgus, isotype Human IgG1-Kappa, source-listed application ELISA.

Product details

Expression system: HEK293
Molecular weight: 49.5 kDa and 23.8 kDa.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: PBS, 10% glycerol (pH 7.4)
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Tezepelumab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Tezepelumab Biosimilar is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human TSLP, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Tezepelumab Biosimilar with the EC50 of 7.2ng/ml determined by ELISA. (QC Test)

Background

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.

References

1.Corren J, Parnes J R, Wang L, et al. Tezepelumab in Adults with Uncontrolled Asthma[J]. New England Journal of Medicine, 2017, 377(10):936-946.

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Anti-TSLP Antibody (Tezepelumab Biosimilar)

Catalog numberTSLP-AB001

HumanHEK293Molecular weight · 49.5 kDa

Anti-TSLP Antibody (Tezepelumab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References

Anti-TSLP Antibody (Tezepelumab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References