Human TM4SF1 VLP Protein

Name: Human TM4SF1 VLP Protein
Brand: Puweituo Bio
SKU: TM4SF1-HP001

Catalog numberTM4SF1-HP001

HumanHEK293Molecule · M3S1; TAAL6; H-L6; L6Molecular weight · 21.64 kDa

Product introduction

Human TM4SF1 VLP Protein is a full-length multi-pass membrane protein presented in a VLP format for antibody discovery, binding assays and method development. Recombinant Human TM4SF1 VLP is expressed from HEK293. It contains Met1-Cys202 (It may have cross reaction with anti-His antibody) (accession: P30408).

Product details

Molecular aliases: M3S1; TAAL6; H-L6; L6
Protein length: Met1-Cys202
Expression system: HEK293
Molecular weight: The target protein has a predicted MW of 21.64 kDa.
Purity: > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Storage: Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.

Background

Transmembrane-4-L-six-family-1(TM4SF1), a four-transmembrane L6 family member, is highly expressed in various pancreatic cancer cell lines and promotes cancer cells metastasis. It is upregulated in several epithelial cancers and is closely associated with poor prognosis.

References

1.Yang JC, Zhang Y, He SJ, Li MM, Cai XL, Wang H, Xu LM, Cao J. TM4SF1 Promotes Metastasis of Pancreatic Cancer via Regulating the Expression of DDR1. Sci Rep. 2017 Apr 3;7:45895. doi: 10.1038/srep45895. PMID: 28368050; PMCID: PMC5377454.

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