PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein

Name: PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein
Brand: Puweituo Bio
SKU: MAGEA1-HP004

Catalog numberMAGEA1-HP004

HumanHEK293Molecule · MAGE-A1

Product introduction

Recombinant PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Tetramer is assembled by biotinylated monomer and PE-Labeled streptavidin It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KVLEYVIKV peptide (accession: A0A140T913(HLA-A*02:01) & P61769(B2M) &KVLEYVIKV).

Product details

Molecular aliases: MAGE-A1; MAGE A1; CT1.1; MAGE-1 antigen; MAGE-1; MZ2-E; MAGE1; MAGE1A
Protein length: Gly25-Thr305
Expression system: HEK293
Formulation: Supplied as 0.22 μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Storage: Valid for 6 months from date of receipt when stored at -80°C; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Background

MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.

References

1.Wang D, Wang J, Ding N, Li Y, Yang Y, Fang X, Zhao H. MAGE-A1 promotes melanoma proliferation and migration through C-JUN activation. Biochem Biophys Res Commun. 2016 May 13;473(4):959-965. doi: 10.1016/j.bbrc.2016.03.161. Epub 2016 Apr 1. PMID: 27045082.

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