Anti-FGFR3 Antibody (Vofatamab Biosimilar)

Name: Anti-FGFR3 Antibody (Vofatamab Biosimilar)
Brand: Puweituo Bio
SKU: FGFR3-AB001

Catalog numberFGFR3-AB001

HumanHEK293Molecular weight · 52.0 kDa

Product introduction

Anti-FGFR3 Antibody (Vofatamab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target FGFR3, reactivity Human, isotype Human IgG1-Kappa, source-listed application ELISA.

Product details

Expression system: HEK293
Molecular weight: 52.0 kDa and 23.3 kDa.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: PBS, 10% glycerol (pH 7.4)
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Vofatamab Biosimilar on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Vofatamab Biosimilar is greater than 95% as determined by SEC-HPLC.

ELISA Data — Immobilized Human FGFR3 alpha (IIIb), His Tag at 1μg/ml (100μl/well) on the plate. Dose response curve for Vofatamab Biosimilar with the EC50 of 5.3ng/ml determined by ELISA. (QC Test)

Background

FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.

References

1.Hadari Y, Schlessinger J. FGFR3-targeted mAb therapy for bladder cancer and multiple myeloma[J]. The Journal of clinical investigation, 2009, 119(5):1077-1079.

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Anti-FGFR3 Antibody (Vofatamab Biosimilar)

Catalog numberFGFR3-AB001

HumanHEK293Molecular weight · 52.0 kDa

Anti-FGFR3 Antibody (Vofatamab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References

Anti-FGFR3 Antibody (Vofatamab Biosimilar)

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

ELISA

ELISA Data

Background

References