Biotinylated Human EDNRA Nanodisc

Name: Biotinylated Human EDNRA Nanodisc
Brand: Puweituo Bio
SKU: EDNRA-HB001

Catalog numberEDNRA-HB001

HumanHEK293Molecule · EDNRAMolecular weight · 61.70 kDa

Product introduction

Recombinant Biotinylated Human EDNRA Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Asn427 (UniProt accession: P25101-1).

Product details

Molecular aliases: EDNRA; ET-A; ETA-R; hET-AR; ETA; ETRA
Protein length: Met1-Asn427
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 61.70 kDa.
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Storage: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

ELISA Data — Immobilized Biotinylated Human EDNRA Nanodisc, His Tag 5μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-EDNRA Antibody, hFc Tag with the EC50 of 0.17μg/ml determined by ELISA. (QC Test)

Background

The endothelin-A receptor (Ednra) is involved in several physiological, pathological, and developmental pathways. Known for its function in vasoconstriction after being activated by endothelin-1, Ednra also controls cephalic neural crest cell development and appears to play a role in several pathologies, including cancer and periodontitis.

References

1.Zhang Y, Knutsen GR, Brown MD, Ruest LB. Control of endothelin-a receptor expression by progesterone is enhanced by synergy with Gata2. Mol Endocrinol. 2013 Jun;27(6):892-908. doi: 10.1210/me.2012-1334. Epub 2013 Apr 16. PMID: 23592430; PMCID: PMC3656236.

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Biotinylated Human EDNRA Nanodisc

Product introduction

Product details

Data display

ELISA

ELISA Data

Background

References

Biotinylated Human EDNRA Nanodisc

Product introduction

Product details

Data display

ELISA

ELISA Data

Background

References