FITC-Labeled Human NKG2D/CD314 Protein

Name: FITC-Labeled Human NKG2D/CD314 Protein
Brand: Puweituo Bio
SKU: CD314-HF002

Catalog numberCD314-HF002

HumanHEK293Molecule · CD314Molecular weight · 43.4 kDa

Product introduction

Recombinant FITC-Labeled Human NKG2D/CD314 Protein is expressed in HEK293 cells with an hFc (IgG1) tag and Flag tag at the N-terminus. It contains amino acid residues Phe78-Val216 (UniProt accession: P26718).

Product details

Molecular aliases: CD314; D12S2489E; KLR; NKG2-D; NKG2D
Protein length: Phe78-Val216
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 43.4 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Formulation: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Storage: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — FITC-Labeled Human NKG2D on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of FITC-Labeled Human NKG2D is greater than 95% as determined by SEC-HPLC.

Background

NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells.

References

1.Spear P, Barber A, Rynda-Apple A, et al. NKG2D CAR T-cell therapy inhibits the growth of NKG2D ligand heterogeneous tumors[J]. Immunology and Cell Biology, 2013, 91(6):435-440.

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FITC-Labeled Human NKG2D/CD314 Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References

FITC-Labeled Human NKG2D/CD314 Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References