Cynomolgus CD24 VLP Protein

Name: Cynomolgus CD24 VLP Protein
Brand: Puweituo Bio
SKU: CD24-CP001

Catalog numberCD24-CP001

HEK293Molecule · CD24Molecular weight · 3.8 kDa

Product introduction

Recombinant Cynomolgus CD24 VLP Protein is produced in HEK293 cells and contains the Ser26-Gly57 region of cynomolgus CD24. The product is supplied as a lyophilized preparation for research use.

Product details

Molecular aliases: CD24; CD24A; CD 24; FLJ22950; FLJ43543; MGC75043
Expression system: HEK293
Molecular weight: 3.8 kDa
Purity: >90% as determined by HPLC
Endotoxin: <1 EU/μg as determined by the LAL method
Formulation: Lyophilized from 0.22 μm filtered PBS, pH 7.4. Normally 8% trehalose is added as a protectant before lyophilization.
State: Lyophilized
Storage: Store at -20°C or below for up to 12 months. Aliquot after reconstitution and minimize freeze-thaw cycles.
Reconstitution: Reconstitute with distilled water. Refer to the Certificate of Analysis for the recommended volume.

Data display

SEC-HPLC Data — The purity of Cynomolgus CD24 VLP is greater than 90% as determined by SEC-HPLC.

Background

CD24 is a sialoglycoprotein expressed on most B lymphocytes and differentiating neuroblasts, as well as on neutrophils and their precursors from the myelocyte stage onward. CD24 is overexpressed in multiple human cancers and is being investigated as a potential therapeutic target.

References

1.Barkal AA et al. CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. Nature. 2019. doi:10.1038/s41586-019-1456-0.
2.Sun F et al. Engineering a high-affinity humanized anti-CD24 antibody to target hepatocellular carcinoma by a novel CDR grafting design. Oncotarget. 2017;8(31):51238-51252.

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Cynomolgus CD24 VLP Protein

Product introduction

Product details

Data display

SEC-HPLC

SEC-HPLC Data

Background

References

Cynomolgus CD24 VLP Protein

Product introduction

Product details

Data display

SEC-HPLC

SEC-HPLC Data

Background

References