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Anti-CD19 Antibody (Coltuximab Biosimilar) is a research-use biosimilar antibody expressed in HEK293. The source page specifies target CD19, reactivity Human, isotype Human IgG1-Kappa, source-listed application ELISA.
CD19 is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses. Functions as coreceptor for the B-cell antigen receptor complex (BCR) on B-lymphocytes. Decreases the threshold for activation of downstream signaling pathways and for triggering B-cell responses to antigens. Activates signaling pathways that lead to the activation of phosphatidylinositol 3-kinase and the mobilization of intracellular Ca2 stores.
