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Recombinant Biotinylated Human STEAP2 VLP is expressed in HEK293 cells. It contains amino acid residues Met1-Met490 (It may have cross reaction with anti-His antibody) (UniProt accession: Q8NFT2-1).
STEAP2, also known as the six transmembrane protein of prostate 1 (STAMP1), is located on chromosome 7q21.13, contains 6 exons and 5 introns, and encodes for a 490 aa long protein with an estimated molecular weight of 56.1 kDa. STEAP2 has been suggested to play a role in protein sorting and secretory pathways, as it shuttles to the Golgi organelle and trans-Golgi network. STEAP2 is significantly overexpressed in prostate cancer when compared to normal healthy tissue.
