Human STEAP1 VLP Protein

Name: Human STEAP1 VLP Protein
Brand: Puweituo Bio
SKU: STEAP1-HP001

Catalog numberSTEAP1-HP001

HumanHEK293Molecule · PRSS24Molecular weight · 43.06 kDa

Product introduction

Human STEAP1 VLP Protein is a full-length multi-pass membrane protein presented in a VLP format for antibody discovery, binding assays and method development. Recombinant Human STEAP1 VLP is expressed from HEK293. It contains Met1-Leu339 (It may have cross reaction with anti-His antibody) (accession: Q9UHE8).

Product details

Molecular aliases: PRSS24; STEAP; PRSS24 / STEAP 1
Protein length: Met1-Leu339
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 43.06 kDa.
Purity: > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Storage: Valid for 12 months from date of receipt when stored at -80°C. Aliquot where appropriate and minimize freeze-thaw cycles.

Background

Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is a cell surface protein of the STEAP family whose main function focuses on intercellular communication and cell growth. STEAP1 is is associated with tumor invasiveness and progression. It is considered a promising putative biomarker and a candidate target for prostate cancer treatment.

References

1.Carvalho M, Gomes RM, Moreira Rocha S, Barroca-Ferreira J, Maia CJ, Guillade L, Correa-Duarte MA, Passarinha LA, Moreira FTC. Development of a novel electrochemical biosensor based on plastic antibodies for detection of STEAP1 biomarker in cancer. Bioelectrochemistry. 2023 Aug;152:108461. doi: 10.1016/j.bioelechem.2023.108461. Epub 2023 May 9. PMID: 37192590.

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