Biotinylated Human SSTR2 Nanodisc

Name: Biotinylated Human SSTR2 Nanodisc
Brand: Puweituo Bio
SKU: SSTR2-HB001

Catalog numberSSTR2-HB001

HumanHEK293Molecule · SS-2-RMolecular weight · 54.30 kDa

Product introduction

Recombinant Biotinylated Human SSTR2 Nanodisc is expressed in HEK293 cells with a His tag at the C-terminus. It contains amino acid residues Met1-Ile369 (UniProt accession: P30874-1).

Product details

Molecular aliases: SS-2-R; SS2-R; SS2R; SRIF-1; SRIF1; SRIF 1; Smstr2; SST2; SSTR2
Protein length: Met1-Ile369
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 54.30 kDa.
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS, 200mM L-arginine (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Storage: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Negative control: CON-HM1NB

Data display

ELISA Data — Immobilized Biotinylated Human SSTR2 Nanodisc, His Tag at 2μg/ml (100μl/well) on the streptavidin precoated plate (5μg/ml). Dose response curve for Anti-SSTR2 Antibody, hFc Tag with the EC50 of 6.0ng/ml determined by ELISA. (QC Test)

SPR Data — Biotinylated Human SSTR2 Nanodisc, His Tag captured on CM5 Chip via Streptavidin can bind Anti-SSTR2 Antibody, hFc-Avi tag with an affinity constant of 0.23 nM as determined in SPR assay (Biacore S200).

Background

Somatostatin receptor (SSTR) 2, widely expressed in meningioma, is a G-protein-coupled receptor and can be activated by somatostatin or its synthetic analogs. SSTR2 is therefore extensively studied as a marker and target for the diagnosis and treatment of meningioma.

References

1.Wu W, Zhou Y, Wang Y, Liu L, Lou J, Deng Y, Zhao P, Shao A. Clinical Significance of Somatostatin Receptor (SSTR) 2 in Meningioma. Front Oncol. 2020 Sep 3;10:1633. doi: 10.3389/fonc.2020.01633. PMID: 33014821; PMCID: PMC7494964.

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Biotinylated Human SSTR2 Nanodisc

Product introduction

Product details

Data display

ELISA

ELISA Data

SPR

SPR Data

Background

References

Biotinylated Human SSTR2 Nanodisc

Product introduction

Product details

Data display

ELISA

ELISA Data

SPR

SPR Data

Background

References