Biotinylated Rat uPAR/PLAUR Protein

Name: Biotinylated Rat uPAR/PLAUR Protein
Brand: Puweituo Bio
SKU: PLAUR-RB001

Catalog numberPLAUR-RB001

RatHEK293Molecule · U-PARMolecular weight · 33.05 kDa

Product introduction

Recombinant Biotinylated Rat uPAR/PLAUR Protein is expressed in HEK293 cells with a His tag and Avi tag at the C-terminus. It contains amino acid residues Leu25-Gly299 (UniProt accession: P49616-1).

Product details

Molecular aliases: U-PAR; uPAR; CD87; PLAUR; MO3; UPAR
Protein length: Leu25-Gly299
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 33.05 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Biotinylated Rat uPAR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Biotinylated Rat uPAR is greater than 95% as determined by SEC-HPLC.

Background

The receptor (u-PAR) for urokinase plasminogen activator (u-PA) is a three-domain protein, GPI-anchored to the cell surface, which focuses the enzymatic activity of u-PA, and allows the cell surface activation of plasminogen. Regulation of the activity of u-PA is also mediated by u-PAR.

References

1.Blasi F. The urokinase receptor and cell migration. Semin Thromb Hemost. 1996;22(6):513-6. doi: 10.1055/s-2007-999053. PMID: 9122717.

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Biotinylated Rat uPAR/PLAUR Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References

Biotinylated Rat uPAR/PLAUR Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References