Biotinylated Human HLA-A*11:01&B2M&MATN2 (KTLTSVFQK) Monomer Protein

Name: Biotinylated Human HLA-A*11:01&B2M&MATN2 (KTLTSVFQK) Monomer Protein
Brand: Puweituo Bio
SKU: MATN2-HB001

Catalog numberMATN2-HB001

HumanHEK293Molecule · MATN2Molecular weight · 50.50 kDa

Product introduction

Recombinant Biotinylated Human HLA-A*11:01&B2M&MATN2 (KTLTSVFQK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and KTLTSVFQK peptide (accession: AAV53343.1(HLA-A*11:01) & P61769(B2M) &KTLTSVFQK).

Product details

Molecular aliases: MATN2; UNQ193/PRO219; Matrilin-2
Protein length: Gly25-Thr305
Expression system: HEK293
Molecular weight: The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Biotinylated Human HLA-A*11:01&B2M&MATN2 (KTLTSVFQK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Biotinylated Human HLA-A*11:01&B2M&MATN2 (KTLTSVFQK) Monomer is greater than 95% as determined by SEC-HPLC.

Background

The matrilins represent a new family of oligomeric proteins that are assumed to act as adapter molecules connecting other proteins and proteoglycans in the extracellular matrix. Matrilin-2, the largest member of the family, is a widely distributed, oligomeric extracellular matrix protein. It incorporates into loose and dense connective tissue and forms a filamentous network by binding to a variety of different extracellular matrix proteins.

References

1.(1) Szabó E, Lódi C, Korpos E, Batmunkh E, Rottenberger Z, Deák F, Kiss I, Tokés AM, Lotz G, László V, Kiss A, Schaff Z, Nagy P. Expression of matrilin-2 in oval cells during rat liver regeneration. Matrix Biol. 2007 Sep;26(7):554-60. doi: 10.1016/j.matbio.2007.04.007. Epub 2007 Apr 21. PMID: 17513098. (2) Wang Z, Luo J, Iwamoto S, Chen Q. Matrilin-2 is proteolytically cleaved by ADAMTS-4 and ADAMTS-5. Molecules. 2014 Jun 23;19(6):8472-87. doi: 10.3390/molecules19068472. PMID: 24959676; PMCID: PMC6271824.

Biotinylated Human HLA-A*11:01&B2M&MATN2 (KTLTSVFQK) Monomer Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References