PE-Labeled Human HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein

Name: PE-Labeled Human HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein
Brand: Puweituo Bio
SKU: MART1-HP005

Catalog numberMART1-HP005

HumanHEK293Molecule · MART1

Product introduction

Recombinant PE-Labeled Human HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin. It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ELAGIGILTV peptide (accession: A0A140T913(HLA-A*02:01) & P61769(B2M) &ELAGIGILTV).

Product details

Molecular aliases: MART1; LB39-AA; SK29-AA; Melan-A; MLANA
Protein length: Gly25-Thr305
Expression system: HEK293
Formulation: Supplied as 0.22μm filtered solution in PBS, 0.2% BSA (pH 7.4).
Storage: Valid for 6 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Background

Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for melanoma.

References

1.Wang J, Jia R, Yao Y, Cun B, Huang X, Gu P, Ge S, Fan X. Differential expression of Mart-1 in human uveal melanoma cells. Mol Med Rep. 2011 Sep-Oct;4(5):799-803. doi: 10.3892/mmr.2011.504. Epub 2011 Jun 7. PMID: 21667026.

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