Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer Protein

Name: Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer Protein
Brand: Puweituo Bio
SKU: HLA-HB001

Catalog numberHLA-HB001

HumanE. coliMolecule · NUTM1Molecular weight · 36.1 kDa

Product introduction

Recombinant Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer Protein is expressed in E. coli with a His tag and Avi tag at the C-terminus. It contains amino acid residues Gly25-Pro307(HLA-A*25:01), Ile21-Met119(B2M) and DVYENFRQW peptide (accession: CDK41178.1(HLA-A*25:01) & P61769(B2M) &DVYENFRQW).

Product details

Molecular aliases: NUTM1; C15orf55; NUT; FAM22H
Protein length: Gly25-Pro307
Expression system: E. coli
Molecular weight: The protein has a predicted MW of 36.1 kDa (HLA-A*25:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Purity: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
Endotoxin: Less than 1 EU per μg by the LAL method.
Formulation: Supplied as 0.22 μm filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Storage: Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Data display

Bis-Tris PAGE Data — Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

SEC-HPLC Data — The purity of Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer is greater than 95% as determined by SEC-HPLC.

Background

Nuclear protein of testis (NUT), a protein product of the NUTM1 gene (located on the long arm of chromosome 15) with highly restricted physiologic expression in post-meiotic spermatids, is the oncogenic driver of a group of emerging neoplasms when fused with genes involved in transcription regulation.

References

1.Luo W, Stevens TM, Stafford P, Miettinen M, Gatalica Z, Vranic S. NUTM1-Rearranged Neoplasms-A Heterogeneous Group of Primitive Tumors with Expanding Spectrum of Histology and Molecular Alterations-An Updated Review. Curr Oncol. 2021 Nov 7;28(6):4485-4503. doi: 10.3390/curroncol28060381. PMID: 34898574; PMCID: PMC8628659.

加载中…

Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer Protein

Catalog numberHLA-HB001

HumanE. coliMolecule · NUTM1Molecular weight · 36.1 kDa

Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References

Biotinylated Human HLA-A*25:01&B2M&NUTM1 (DVYENFRQW) Monomer Protein

Product introduction

Product details

Data display

Bis-Tris PAGE

Bis-Tris PAGE Data

SEC-HPLC

SEC-HPLC Data

Background

References